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產(chan)品(pin)名稱:A2ti-2 482646-13-9
規(gui)格:10mM*1 mL in DMSO、5 mg、10 mg、25 mg、50 mg、100 mg
貨號(hao):GOY-01Y64608
Cas No.: 482646-13-9
別(bie)名: N/A
化(hua)學名: N/A
分子(zi)式: C18H18N4O2S

分子(zi)量(liang): 354.43
溶(rong)解度(du): DMSO : 250 mg/mL (705.36 mM)
儲存條件: Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chan)品(pin)說(shuo)明:
A2ti-2 is a selective and low-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 230 µM[1]. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-2 prevents human papillomavirus type 16 (HPV16) infection[2].A2ti-2 (compound 7a) is an annexin A2-S100A10 protein-protein interaction blocker[1]. A2ti-2 is less effective with <50% reduction in HPV16 PsV infection achieved at 100 µM. A2ti-1 decreases HPV16 entry with a 20% reduction at 100 µM[2].
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